Clinical and Translational Science Research Program
Clinical and Translational Science Research Program
The Clinical and Translational Science Institute (CTSI) at The Ohio State University is accepting applications for the 2025 Clinical and Translational Science Research Program Award, funded by the National Institutes of Health's (NIH) National Center for Advancing Translational Sciences (NCATS) Clinical and Translational Science Awards (CTSA) Program. The goal of this award is to fund a highly meritorious interdisciplinary clinical and translational science (CTS) project that develops AI tools that advance health for all.
Successful translational science studies can emphasize specific clinical and translational research area, but must be designed to develop or test a translational science-directed hypothesis with potential for broader application that addresses a barrier to the progression of turning observations in the laboratory, clinic and community into interventions that improve the health of individuals or the population health. Through employing one or more translational science principles, a translational science-directed hypothesis should generate a scientific, operational, financial or administrative innovation that addresses longstanding challenges along the translational research pipeline, transforming the way that research is done, making it faster, more efficient and more impactful. More information on translational science and the scientific and operational principles of translational science can be found here.
Funding per Award
Up to $125,000 annually for two years direct costs
Pre-Application Due Date
September 30, 2025
Submission window open: September 20 - 30, 2025
Invited Full Application Due Date
November 17, 2025
Proposals must develop new concepts, methods, technologies or research practices that drive translational science, and should clearly identify the translational science challenges or barriers that their proposal addresses.
Proposed work must be innovative, equitable and generalizable.
Proposed work must be completed within two years. The NIH does not allow no cost extensions on these funds. Feasibility for completing the work within 24 months will be an important review criterion.
Optional Information Session
Monday, September 8, 2025, 4 - 5 p.m., Virtual
The award program’s co-directors and program manager will host an information session that includes Q&A with participants. A link to a recording of it will be posted to the CTSI website.
Optional Proposal Ideation Workshop
Friday, September 12, 2025, 10 a.m. - noon, Virtual
Prospective applicants have the opportunity to present proposal ideas in a virtual workshop designed to elevate the strength and quality of proposals through early peer and panel feedback. Attendees will include a mock review panel to provide expert comments, and other members of the Ohio State University and Nationwide Children’s Hospital community.
Participation in this ideation workshop is not a prerequisite for application to the RFA, and feedback in this workshop is not indicative of application success.
Up to 15 presentations will be accommodated in the workshop, on a first come, first served basis.
To participate as a presenter, choose the "presenter" option in the registration form and come prepared to share a three-minute presentation that includes:
- Translational science research question(s)
- Research strategy, including data management plan and rigor of the study
- Significance to clinical and translational science
2025 Funded Projects
Project 1
AI-guided information retrieval and recommendation for clinical decision support. (MPI: Drs. Xia Ning and Courtney Hebert, Department of Biomedical Informatics, College of Medicine)
Project 2
Unleashing the Potential of Large Language Models for Clinical and Translational Science: Application to Addressing Unmet Social Needs of Patients (MPI: Drs. Macarius Donneyong, Huan Sun, and Yu Su, College of Pharmacy and College of Engineering)
Primary Contacts
Lang Li
Program Co-Director of the Clinical and Translational Science Research Program, Professor and Chair of the Department of Biomedical Informatics
Tanya Berger Wolf
Program Co-Director of the Clinical and Translational Science Research Program, Director of the Translational Data Analytics Institute and Professor of Computer Science and Engineering, Electrical and Computer Engineering and Evolution, Ecology and Organismal Biology
Jenny Grabmeier
Program Manager of the Clinical and Translational Science Research Program, Director of Research Strategy at the Translational Data Analytics Institute